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The recommended practice of applying silicone to hypertrophic scars post-surgery when the scar is hypersensitive involves nighttime application. During the night, the body is in a more relaxed state, which can help enhance the effectiveness of silicone in forming a protective barrier over the scar, reducing sensitivity and irritation. Additionally, nighttime application ensures that the silicone remains in contact with the scar for an extended period without the interruptions that might occur during daily activities.

Using silicone continuously can have different effects; the adhesive properties of silicone sheets or gels are best utilized when applied for longer durations, supporting the healing environment conducive to scar remodeling. In cases where patients report hypersensitivity, applying silicone at night gives the scar a chance to heal without additional discomfort or exposure to external irritants during the day. This approach balances the need for consistent silicone application with the patient's comfort level, making it an effective strategy in hypertrophic scar management.